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Invitrogen™ PADI2 Monoclonal Antibody (K40045_12F1), Invitrogen™

Catalog No. MA556168
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200 μL
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MA556168 200 μL
MA555788 50 μL
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Catalog No. MA556168 Supplier Invitrogen™ Supplier No. MA556168
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: SLKHSEHVWV EVVRDGEAEE VATNGKQRWL LSPSTTLRVT MSQASTEASS DKVTVNYYDE EGSIPIDQAG LFLTAIEISL

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Specifications

Antigen PADI2
Applications Western Blot
Classification Monoclonal
Clone K40045_12F1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene PADI2
Gene Accession No. Q9Y2J8
Gene Alias KIAA0994; mKIAA0994; PAD type II; Pad2; PAD-H19; PADI2; Pdi; PDI2; peptidyl arginine deiminase 2; peptidyl arginine deiminase, type 2; peptidyl arginine deiminase, type II; peptidyl arginine deiminase, type II; PAD type II; peptidylarginine deiminase II; Protein-arginine deiminase type II; protein-arginine deiminase type-2; RP1-37C10.6
Gene Symbols PADI2
Host Species Mouse
Immunogen Recombinant human PADI2 (immunogen range is 41-120).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11240
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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