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Invitrogen™ P2X6 Polyclonal Antibody
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Catalog No. PIPA5116436
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Catalog No. Quantity
PIPA5116436 100 μL
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Catalog No. PIPA5116436 Supplier Invitrogen™ Supplier No. PA5116436
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Description

Rabbit Polyclonal Antibody

Positive controls: Jurkat cell lysate, K562 cell lysate, rat skeletal muscle tissue, rat brain tissue, mouse skeletal muscle tissue, mouse heart tissue, SH-SY5Y.

P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. The P2rx6 gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2rx6.

Specifications

Antigen P2X6
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene P2RX6
Gene Accession No. O15547, O54803, P51579
Gene Alias ATP receptor; P2RX6; P2RXL1; P2X purinoceptor 6; P2x6; P2X6 receptor; P2XM; Purinergic receptor; purinergic receptor P2X 6; purinergic receptor P2X, ligand gated ion channel, 6; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor P2X6; Purinergic receptor P2X-like 1; purinergic receptor P2X-like 1 orphan receptor; purinergic receptor P2X-like 1, orphan receptor; purinoceptor P2X6; purinoreceptor P2X6; Rnap2x6; skeletal muscle-expressed P2X
Gene Symbols P2RX6
Host Species Rabbit
Immunogen Synthetic peptide within rat P2rx6 aa 340-389.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18440, 25041, 9127
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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