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Invitrogen™ NUMB Recombinant Rabbit Monoclonal Antibody (23GB940)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA554229
Description
NUMB Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.Specifications
| NUMB | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Numb | |
| c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 18222, 29419, 8650 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB940 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P49757, Q2LC84, Q9QZS3 | |
| Numb | |
| A synthetic peptide of human NUMB (1-47AA). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |