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Invitrogen™ NOX1 Polyclonal Antibody
GREENER_CHOICE

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142645

Catalog No. PIPA5142645


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Description

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_008983.2; NP_39249.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
Specifications

Chemical Identifiers

NOX1
-20°C, Avoid Freeze/Thaw Cycles
Polyclonal
Liquid
IgG
Human
Nox1
GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Nox1
Primary
Ammonium sulfate precipitation
0.5 mg/mL
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Goat
RUO
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q9Y5S8
27035
Peptide with sequence C-DKATDIVTGLKQK (aa 490-502).
Antibody

Specifications

NOX1
Polyclonal
Unconjugated
Nox1
GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Goat
Ammonium sulfate precipitation
RUO
27035
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q9Y5S8
Nox1
Peptide with sequence C-DKATDIVTGLKQK (aa 490-502).
100 μg
Primary
Human
Antibody
IgG
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