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Invitrogen™ NMDAR1 Polyclonal Antibody
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Catalog No. OPA104011
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25 μg
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Catalog No. Quantity
OPA104011 25 μg
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Catalog No. OPA104011 Supplier Invitrogen™ Supplier No. OPA104011

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with canine, chicken, human, non-human primate and Xenopus based on 100% sequence homology. In Western blot, this antibody detects an ~100 kDa protein representing the NR1 N1 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 C1, C2, or C2 splice variants. Reconstitute with 50 μL of PBS. After reconstitution the antibody should be aliquotted and stored at -20ºC.

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Specifications

Antigen NMDAR1
Applications Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation 5mM Ammonium bicarbonate with no preservative
Gene GRIN1
Gene Accession No. P35438, P35439
Gene Alias GluN1; Glun1r; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
Gene Symbols GRIN1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, N1 splice variant insert conjugated to KLH.
Purification Method Affinity Chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14810, 24408
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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