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Invitrogen™ NFIB Monoclonal Antibody (1H1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA545062
Description
NFIB Monoclonal Antibody for IHC (P), Flow
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.Specifications
| NFIB | |
| Monoclonal | |
| 2 mg/mL | |
| PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| O00712, P97863 | |
| NFIB | |
| Recombinant full length protein corresponding to human NFIB/NF1B2. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2b |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| 1H1 | |
| Unconjugated | |
| NFIB | |
| 6720429L07Rik; CCAAT-box-binding transcription factor; CTF; E030026I10Rik; HMGIC/NFIB; NF1-B; NF-I/B; Nfib; NFI-B; NFIB2; NFIB3; NFI-RED; nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I B; nuclear factor I/B; olfactory epithelium nuclear factor I-B; TGGCA-binding protein | |
| Mouse | |
| Antigen Affinity Chromatography | |
| RUO | |
| 18028, 29227, 4781 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |