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Invitrogen™ NFAT5 Monoclonal Antibody (K49018_1C5), Invitrogen™

Catalog No. MA556149
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200 μL
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MA556149 200 μL
MA555769 50 μL
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Catalog No. MA556149 Supplier Invitrogen™ Supplier No. MA556149
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: GQYPVKSEGK ELKIVVQPET QHRARYLTEG SRGSVKDRTQ QGFPTVKLEG HNEPVVLQVF VGNDSGRVKP HGFYQACRVT GRNTTPCKEV DIEGTTVIEV GLDPSNNMTL AVDCVGILKL RNADVEARIG IAGSKKKSTR ARLVFRVNIM RKDGSTLTLQ TPSSPILCTQ PAGVPEILKK SLHSCSVKGE EEVFLIGKNF LKGTKVIFQE NVSDENSWKS EAEIDMELFH QNHLIVKVPP YHDQHITLPV SVGIYVVTNA GRSHDVQPFT

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.

Specifications

Antigen NFAT5
Applications Western Blot
Classification Monoclonal
Clone K49018_1C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene NFAT5
Gene Accession No. O94916
Gene Alias AI225870; B130038B15Rik; CAG-8; CAG80; glutamine rich protein H65; KIAA0827; mKIAA0827; Nfat; Nfat5; NF-AT5; NFATL1; NFAT-like protein 1; nfatz; nuclear factor of activated T cells 5; nuclear factor of activated T-cells 5; nuclear factor of activated T-cells 5, tonicity-responsive; OREBP; osmotic response element-binding protein; rel domain-containing transcription factor NFAT5; T-cell transcription factor NFAT5; TonE-binding protein; TONEBP; tonicity-responsive enhancer binding protein; tonicity-responsive enhancer-binding protein
Gene Symbols NFAT5
Host Species Mouse
Immunogen Recombinant human NFAT5 (immunogen range is 271-540).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10725
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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