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Neomycin sulfate hydrate
CAS: 1405-10-3 | C23H48N6O17S | 712.72 g/mol
Supplier: Thermo Scientific Chemicals J6149914
Description
Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsNeomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
Solubility
Soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications
| Neomycin Sulfate | |
| Powder | |
| White | |
| C23H48N6O17S | |
| 14,6454 | |
| OIXVKQDWLFHVGR-DJUBFIBWNA-N | |
| 5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-[(3,5-diamino-2-{[3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl)oxy]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol; sulfuric acid | |
| 124080932 |
| Neomycin sulfate hydrate | |
| 1405-10-3 | |
| 25 g | |
| MFCD29905465 | |
| Soluble in water | |
| OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O | |
| 712.72 | |
| 908.87 (Anhydrous) |
Chemical Identifiers
| 1405-10-3 | |
| 712.72 | |
| OIXVKQDWLFHVGR-DJUBFIBWNA-N | |
| OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O |
| C23H48N6O17S | |
| MFCD29905465 | |
| 124080932 |
Safety and Handling
GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
P201-P202-P260-P272-P280g-P281-P285-P302+P352-P304+P341-P308+P313-P333+P313-P342+P311-P363-P501c
H317-H334-H361d-H373
EINECSNumber : 215-773-1
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only