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Invitrogen™ Human NEK2, His Tag Recombinant Protein
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.
Specifications
Specifications
| Accession Number | P51955 |
| Concentration | See Label |
| For Use With (Application) | Kinase Assay |
| Formulation | 50mM tris with 500mM NaCl, 0.5mM EDTA, 0.05% Triton X-100, 50% glycerol, 2mM DTT and no preservative; pH 7.5 |
| Gene ID (Entrez) | 4751 |
| Molecular Weight (g/mol) | 54.5 kDa |
| Name | Human NEK2, His Tag |
| pH Range | 7.5 |
| Purification Method | Purified |
| Quantity | 10 μg |
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