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Invitrogen™ NBS1 Monoclonal Antibody (1C3)
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Catalog No. PIMA123263
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100 μL
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Catalog No. Quantity
PIMA123263 100 μL
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Catalog No. PIMA123263 Supplier Invitrogen™ Supplier No. MA123263
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Description

Mouse Monoclonal Antibody

Recommended positive controls: 293T, MCF7, HeLa, Raji.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

Antigen NBS1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1C3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and no preservative; pH 7
Gene NBN
Gene Accession No. O60934, Q9R207
Gene Alias AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Gene Symbols NBN
Host Species Mouse
Immunogen The complete coding region of the human p95/NBS1 expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27354, 4683
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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