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Invitrogen™ Narsoplimab Recombinant Human Monoclonal Antibody
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Catalog No. PIMA542178
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100 μg
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Catalog No. Quantity
PIMA542178 100 μg
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Catalog No. PIMA542178 Supplier Invitrogen™ Supplier No. MA542178
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Description

Human Recombinant Monoclonal Antibody

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Narsoplimab is a human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the lectin pathway of the complement system. The lectin pathway is one of the principal pathways of complement and is activated primarily by tissue damage and microbial infection. Importantly, inhibition of MASP-2 does not appear to interfere with the classical complement pathway, a critical component of the acquired immune response to infection. This novel, proprietary pharmaceutical is designed to prevent complement-mediated inflammation and endothelial damage while leaving intact the respective functions of the other pathways of innate immunity.

Specifications

Antigen Narsoplimab
Applications ELISA, SDS-Page
Classification Recombinant Monoclonal
Concentration 2.59 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Alias OMS721
Host Species Human
Immunogen Human MASP2.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG4 λ
Target Molecule Chemical
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