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Nalidixic acid, 99.5%
Nalixidic acid, or nalixidin, CAS # 389-08-2, is a quinolone antibiotic used to inhibit DNA gyrase and prevent cell division. | CAS: 389-08-2 | C12H12N2O3 | 232.24 g/mol
Supplier: Thermo Scientific Chemicals 169900050
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Nalixidic acid is a synthetic quinolone that is a monocarboxylic acid composed of 1,8-naphthyridine substituted with carboxylic acid, ethyl, and methyl groups
• Nalixidic acid is a DNA gyrase inhibitor that prevents DNA synthesis and subsequent cell divisions
Applications
• Nalixidic acid is primarily effective against gram-negative bacteria
• It may be useful for bacterial resistance studies and laboratory research on drug allergies and cross-reactivity
• Nalixidic acid is suitable for high-performance liquid chromatography (HPLC) and related biochemistry laboratory applications
Specifications
| Nalidixic acid | |
| 389-08-2 | |
| 100.0 | |
| White to Yellow | |
| 99.5% | |
| C12H12N2O3 | |
| 5 g | |
| 15, 6444 | |
| Solubility in water: 0.1g/L (23°C). Other solubilities: soluble in alkali solutions,35mg/mL chloroform- 1.6mg/mL toluene (23°C),1.3mg/mL methanol- 0.9mg/mL ethanol (23°C),0.1mg/mL ether (23°C) | |
| CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O | |
| 232.24 | |
| CHEBI:100147 | |
| 99.5% |
| 99.5% | |
| 99.4 | |
| 225.0°C to 231.0°C | |
| Authentic | |
| Glass bottle | |
| MFCD00006884 | |
| 25, V,7, 384 | |
| nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus | |
| MHWLWQUZZRMNGJ-UHFFFAOYSA-N | |
| 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid | |
| 4421 | |
| 232.24 | |
| Powder |
Chemical Identifiers
| 389-08-2 | |
| 232.24 | |
| MHWLWQUZZRMNGJ-UHFFFAOYSA-N | |
| 4421 | |
| 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid |
| C12H12N2O3 | |
| MFCD00006884 | |
| nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus | |
| CHEBI:100147 | |
| CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O |
Safety and Handling
GHS H Statement
May cause an allergic skin reaction.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
Wear eye protection/face protection.
GHS Signal Word: Danger
EINECSNumber : 206-864-7
RTECSNumber : QN2885000
RUO – Research Use Only