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Invitrogen™ Myotilin Polyclonal Antibody

Description
Recommended positive controls: A549. Predicted reactivity: Mouse (93%), Rat (94%), Pig (95%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Specifications
Specifications
| Antigen | Myotilin |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | MYOT |
| Gene Accession No. | Q9UBF9 |
| Gene Alias | 5530402I04Rik; 57 kDa cytoskeletal protein; LGMD1; LGMD1A; MFM3; Myo; Myofibrillar titin-like Ig domains protein; MYOT; Myotilin; titan-like protein; titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin); Ttid; TTOD |
| Gene Symbols | MYOT |
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