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Invitrogen™ MTHFD2 Monoclonal Antibody (K70015_2H12), Invitrogen™

Catalog No. MA555898
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200 μL
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MA555898 50 μL
MA556278 200 μL
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Catalog No. MA555898 Supplier Invitrogen™ Supplier No. MA555898
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: TIMKPASISE EELLNLINKL NNDDNVDGLL VQLPLPEHID ERRICNAVSP DKDVDGFHVI NVGRMCLDQY SMLPATPWGV WEIIKRTGIP TLGKNVVVAG RSKNVGMPIA MLLHTDGAHE RPGGDATVTI SHRYTPKEQL KKHTILADIV ISAAGIPNLI TADMIKEGAA VIDVGINRVH DPVTAKPKLV GDVDFEGVRQ

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

Specifications

Antigen MTHFD2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K70015_2H12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene MTHFD2
Gene Accession No. P13995
Gene Alias AW558851; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 2; Mthfd2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC
Gene Symbols MTHFD2
Host Species Mouse
Immunogen Recombinant human MTHFD2 (immunogen range is 101-300).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10797
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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