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Invitrogen™ MRP3 Polyclonal Antibody

Description
Immunogen sequence: FLPQTDFIIV LADGQVSEMG PYPALLQRNG SFANFLCNYA PDEDQGHLED SWTALEGAED KEALLIEDTL SNHTDLTDND PVTYVVQKQF MRQLSALSSD GEGQGRPVPR RHLGPSEKVQ VTEAKADGAL T Highest antigen sequence indentity to the following orthologs: Mouse - 64%, Rat - 61%.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Specifications
Specifications
| Antigen | MRP3 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | ABCC3 |
| Gene Accession No. | O15438 |
| Gene Alias | ABC31; ABCC3; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; cMOAT2; DKFZp686E22157; EST90757; MLP2; MLP-2; MOAT-D; Mrp3; MRP-like protein 2; multidrug resistance associated protein; multidrug resistance protein 3; multidrug resistance-associated protein 3; multi-specific organic anion transporter D; organic anion transporter |
| Gene Symbols | ABCC3 |
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