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Invitrogen™ MRGD Polyclonal Antibody
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Catalog No. PIPA533944
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50 μg
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Catalog No. Quantity
PIPA533944 50 μg
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Catalog No. PIPA533944 Supplier Invitrogen™ Supplier No. PA533944
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon (89%) Marmoset (83%).

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

Specifications

Antigen MRGD
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene MRGPRD
Gene Accession No. Q8TDS7
Gene Alias Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MrgD; MRGD G protein-coupled receptor; MRGPRD; TGR7
Gene Symbols MRGPRD
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human MRGPRD.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116512
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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