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Invitrogen™ Mouse P1NP ELISA Kit

Catalog No. EEL220
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96 Tests
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EEL220 96 Tests
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Catalog No. EEL220 Supplier Invitrogen™ Supplier No. EEL220
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Description

ELISA

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

Specifications

Accession Number P11087
Assay Range 93.75 to 6000 pg/mL
Assay Sensitivity 56.25 pg/mL
Conjugate HRP
Detection Method Colorimetric
Immunoassay Kit Format ELISA Microplate (Dismountable)
Product Type ELISA
Sample Type Plasma, Serum
Target Species Mouse
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 12842
Gene Symbol COL1A1
Interassay CV <10
Intraassay CV <10
Kit Contents Micro ELISA Plate (Dismountable), Reference Standard, Concentrated Biotinylated Detection Ab(100x), Concentrated HRP Conjugate (100x), Reference Standard & Sample Diluent, Biotinylated Detection Ab Diluent, HRP Conjugate Diluent, Concentrated Wash Buffer(25x), Substrate Reagent, Stop Solution, Plate Sealer, Product Description, Certificate of Analysis
Label or Dye Biotin
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma: 100 μL, Serum: 100 μL
Storage Requirements Refer to product documentation for component specific storage temperature.
Target Procollagen I N-Peptide
Test Time 1 hr. 20 min.
Total Assay Time 3 hr. 30 min.
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