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Gibco™ Mouse IL-4 Recombinant Protein
Description
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Lyophilized mIL-4 should be reconstituted in sterile, 10 mM HAc not less than 100 μg/mL, which can then be further diluted to other aqueous solutions. For long term storage, it is recommended to add a carrier protein, such as 0.1% HSA or BSA. Storage: This lyophilized preparation is stable at room temperature for 3 weeks, but should be stored desiccated below -18°C. Upon reconstitution, the preparation is stable at 4°C for up to 1 week, but should be stored below -18°C for long term storage. Avoid repeated freeze/thaw cycles.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Spécifications
Spécifications
| Numéro d'enregistrement | P07750 |
| À utiliser avec (application) | Bioactivity |
| Formule | PBS with no preservative; pH 7.4 |
| ID du gène (Entrez) | 16189 |
| Poids moléculaire (g/mol) | 13.5 kDa |
| Nom | Mouse IL-4 |
| Plage de pH | 7.4 |
| Méthode de purification | Purified |
| Quantité | 10 μg |
| Conditions de stockage | -20°C |
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