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Invitrogen™ Monkey IGFBP-3 ELISA Kit
Description
Monkey IGFBP-3 quantitates monkey IGFBP-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey IGFBP-3.
IGFBP3 is a gene that belongs to the insulin-like growth factor binding protein (IGFBP) family. The gene encodes a protein that contains both an IGFBP domain and a thyroglobulin type-I domain. This protein is known to form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. The complex circulates in the plasma and prolongs the half-life of IGFs while also altering their interaction with cell surface receptors. Various isoforms of the gene have been identified through alternate transcriptional splice variants. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.
Specifications
Specifications
| Accession Number | acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; I79 |
| Assay Range | 1.024 to 250 ng/mL |
| Assay Sensitivity | 1.02 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Interassay CV | <12% |
| Intraassay CV | <10 |
| Kit Contents | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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