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Invitrogen™ MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Brilliant Ultra Violet™ 496, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$297.00 - $554.00
Specifications
| Antigen | MHC Class II (I-A/I-E) |
|---|---|
| Clone | M5/114.15.2 |
| Concentration | 0.2 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
Description
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.Specifications
| MHC Class II (I-A/I-E) | |
| 0.2 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| Abeta; AI323765; AI845868; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; H2-IE-alpha; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia3; Ia-3; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II antigen E alpha; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1 | |
| H2-Aa, H2-Ab1, H2-Eb1 | |
| Primary | |
| 4°C, store in dark, DO NOT FREEZE! | |
| H2-Ab1 |
| M5/114.15.2 | |
| Flow Cytometry | |
| Brilliant Ultraviolet 496 | |
| Rat | |
| Mouse | |
| P01910, P01921, P04227, P04228, P04230, P06342, P06343, P06344, P06345, P06346, P14434, P14435, P14436, P14437, P14438, P14483, P23150 | |
| 14960, 14961, 14969 | |
| IgG2b κ | |
| Affinity chromatography | |
| Antibody |