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Invitrogen™ MEKK2 Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Specifications
Specifications
| Antigen | MEKK2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Map3k2 |
| Gene Accession No. | Q61083, Q9Y2U5 |
| Gene Alias | 2.7.11.25; 9630061B06Rik; AI585793; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b |
| Gene Symbols | Map3k2 |
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