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Invitrogen™ MCRS1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5119815
Description
Positive Control: SH-SY5Y cell lysates, rat large intestine tissue, human liver tissue, human pancreas tissue, mouse testis tissue. Subcellular Location: Nucleus, Nucleolus, Cytoplasm.
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602). [UniProt].Chemical Identifiers
| MCRS1 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| MCRS1 | |
| 58 kDa microspherule protein; C78274; cell cycle-regulated factor (78 kDa); cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; INO80 complex subunit Q; INO80Q; Mcrs1; MCRS2; Microspherule protein 1; MSP58; nucleolar protein; P78 | |
| MCRS1 | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q96EZ8, Q99L90 | |
| 10445, 300222, 51812 | |
| Recombinant protein within human MCRS1 aa 1-200. | |
| Antibody |
Specifications
| MCRS1 | |
| Polyclonal | |
| Unconjugated | |
| MCRS1 | |
| 58 kDa microspherule protein; C78274; cell cycle-regulated factor (78 kDa); cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; INO80 complex subunit Q; INO80Q; Mcrs1; MCRS2; Microspherule protein 1; MSP58; nucleolar protein; P78 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10445, 300222, 51812 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q96EZ8, Q99L90 | |
| MCRS1 | |
| Recombinant protein within human MCRS1 aa 1-200. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |