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  6. Invitrogen™ MCM7 Recombinant Rabbit Monoclonal Antibody (23GB930)

Invitrogen™ MCM7 Recombinant Rabbit Monoclonal Antibody (23GB930)

Catalog No. MA554063
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100 μL
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MA554063 20 μL
MA554062 100 μL
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Catalog No. MA554063 Supplier Invitrogen™ Supplier No. MA554063
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Description

Rabbit Recombinant Monoclonal Antibody

MCM7 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

Antigen MCM7
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB930
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Mcm7
Gene Accession No. P33993
Gene Alias AI747533; CDC47; CDC47 homolog; CDC47 homolog A; CDC47p; DNA replication licensing factor MCM7; DNA replication licensing factor mcm7-A; DNA replication licensing factor MCM7-like protein; homolog of S. cerevisiae Cdc47; mCDC47; MCM2; MCM7; MCM7 minichromosome maintenance deficient 7; mcm7.S; mcm7-a; mcm7-b; Mcmd7; mini chromosome maintenance deficient 7; minichromosome maintenance complex component 7; minichromosome maintenance complex component 7 S homeolog; minichromosome maintenance deficient 7; minichromosome maintenance deficient 7 (S. cerevisiae); minichromosome maintenance protein 7; minichromosome maintenance protein 7-A; P1 P85MCM; P1.1-MCM3; P1CDC47; P85MCM; p90; PNAS146; PPP1R104; protein phosphatase 1, regulatory subunit 104; Unknown (protein for MGC:128845); XELAEV_18000877mg; XMCM7; xMCM7-A
Gene Symbols Mcm7
Host Species Rabbit
Immunogen A synthetic peptide of human MCM7 (1-50AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 288532, 4176
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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