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Invitrogen™ Matuzumab Chimeric Recombinant Mouse Monoclonal Antibody (Matuzumab)
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Catalog No. MA551719
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200 μg
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Catalog No. Quantity
MA551719 200 μg
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Catalog No. MA551719 Supplier Invitrogen™ Supplier No. MA551719
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Description

Mouse Recombinant Monoclonal Antibody

This antibody binds the extracellular domain III of the human EGFR and does not cross react with murine EGFR. It was also reported that residues S460/G461 in EGFR domain III are essential components of the epitope.

Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR, frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival.

Specifications

Antigen Matuzumab Chimeric
Applications ELISA, Flow Cytometry, Inhibition Assays, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone Matuzumab
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Alias EMD-72000; H425
Host Species Mouse
Immunogen The parental mouse antibody was generated by immunizing BALB/c mice intraperitoneally with A431 cells in phosphate buffered saline (PBS). Later on the humanzied version of the antibody was created by grafting CDRs of the murine antibody onto human constant regions.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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