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Invitrogen™ MAGEA3 Chimeric Recombinant Rabbit Monoclonal Antibody (21B4)
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Catalog No. MA551710
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200 μg
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Catalog No. Quantity
MA551710 200 μg
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Catalog No. MA551710 Supplier Invitrogen™ Supplier No. MA551710
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody binds human MAGEA3 and MAGEA6, but does not cross react with other members of the MAGE family like MAGE-A1, MAGE-A4 and MAGE-A10. MAGE-A3 is a tumor specific antigen and it is expressed on many tumors like melanoma, non-small cell lung cancer, hematologic malignancies, and others.

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Specifications

Antigen MAGEA3 Chimeric
Applications ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 21B4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene MAGEA3
Gene Accession No. P43357
Gene Alias Antigen MZ2-D; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; CT1.3; HIP8; HYPD; MAGE family member A3; MAGE3; MAGE-3 antigen; MAGEA3; Mage-a3; MAGEA6; melanoma antigen family A, 3; melanoma antigen family A3; melanoma antigen, family A, 3; melanoma-associated antigen 3; MGC14613
Gene Symbols MAGEA3
Host Species Rabbit
Immunogen The original antibody was isolated from a patient suffering from a tumor expressing a tumor specific antigen like MAGE-A3.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4102
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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