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Cytiva MabSelect™ Chromatography Media

Catalog No. 45002370
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25 mL
200 mL
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45002370 25 mL
45002978 200 mL
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Catalog No. 45002370 Supplier Cytiva Supplier No. 17519901
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Description

Protein A affinity medium designed for capturing MAbs from large sample volumes

  • High-flow agarose matrix allows for high flow velocities at production scale
  • BioProcess medium supported for industrial applications and well-established in approved processes
  • Low non-specific binding resulting in low levels of impurities in the product eluate pool
  • Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity
  • Based on highly cross-linked agarose matrix with recombinant protein A ligand
  • Ligand is engineered to favor oriented coupling and expressed in E. coli and is free of components of mammalian origin
  • Hydrophilic nature of the base matrix ensures low levels of non-specific

  • Average particle size: 85μm (d50V)
  • pH Stability cleaning-in-place (CIP): 2 to 12
  • pH Stability working range: 3 to 10
  • Ligand: recombinant protein A (E.coli)
  • Matrix: highly cross-linked agarose
  • Binding capacity/mL chromatography medium: ∽30mg human lgG/mL at 2.4 min. residence time
  • Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm

Specifications

Quantity 25 mL
For Use With (Application) For Industrial AppliCatIons and Well-Established in Approved Processes
Storage Requirements 2°C to 8°C
Binding Capacity 30 mg Human lgG/mL (at 2.4 min. residence time)
Product Type MabSelect Media
Flow Rate <500 cm/Hoμr
Particle Size 85 μm
Height (English) Bed 7.87 in.
Height (Metric) Bed 20 cm
Includes Certificate of Analysis
Max. Pressure <200 kPa
Matrix Highly Cross-Linked Agarose
pH Range 3 to 10
Ligand Type Recombinant Protein A (E. coli)
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