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Loratadine, 98+%

Catalog No. p-7058181
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Quantity:
1 g
5 g
500 mg
Catalog No. Quantity
AAJ60190ME 500 mg
AAJ6019003 1 g
AAJ6019006 5 g
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Catalog No. AAJ60190ME

Supplier: Thermo Scientific Chemicals J60190ME

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Description

A nonsedating-type histamine H1-receptor antagonist | CAS: 79794-75-5 | C22H23ClN2O2 | 382.888 g/mol

Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Chemical Identifiers

CAS 79794-75-5
Molecular Formula C22H23ClN2O2
Molecular Weight (g/mol) 382.888
MDL Number MFCD00672869
InChI Key JCCNYMKQOSZNPW-UHFFFAOYSA-N
Synonym loratadine, claritin, loratidine, alavert, clarityn, lisino, clarityne, loracert, loradex, bonalerg
PubChem CID 3957
IUPAC Name ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
SMILES CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

Specifications

Melting Point 134°C
Color White
Quantity 500 mg
Merck Index 14,5578
Solubility Information It is soluble in DMSO (50mg/ml),ethanol (77mg/ml at 25°C),water (<1mg/ml at 25°C),chloroform,and methanol.
Formula Weight 382.88
Percent Purity ≥98%
Physical Form Powder
Chemical Name or Material Loratadine

Safety and Handling

RTECSNumber TM6129200
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only