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Invitrogen™ LNK Polyclonal Antibody

Description
Antibody detects endogenous levels of total SH2B3.
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
Specifications
Specifications
| Antigen | LNK |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | SH2B3 |
| Gene Accession No. | Q9UQQ2 |
| Gene Alias | AI429800; IDDM20; linker of T-cell receptor pathways; LNK; Lymphocyte adapter protein; lymphocyte-specific adapter protein Lnk; SH2B adapter protein 3; SH2B adaptor protein 3; Sh2b3; Signal transduction protein Lnk |
| Gene Symbols | SH2B3 |
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