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Invitrogen™ LMX1B Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA5142403
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.Specifications
| LMX1B | |
| Polyclonal | |
| Unconjugated | |
| Lmx1b | |
| LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 4010 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| O60663 | |
| Lmx1b | |
| Peptide with sequence QQALTTSCYFRDRK. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |