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Invitrogen™ LMAN1 Polyclonal Antibody
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Catalog No. PIPA5113826
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100 μL
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Catalog No. Quantity
PIPA5113826 100 μL
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Catalog No. PIPA5113826 Supplier Invitrogen™ Supplier No. PA5113826

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DPAVALPHRR FEYKYSFKGP HLVQSDGTVP FWAHAGNAIP SSDQIRVAPS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%.

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Specifications

Antigen LMAN1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene LMAN1
Gene Accession No. P49257
Gene Alias 2610020P13Rik; AI326273; AU043785; C730041J05; EGK_09725; endoplasmic reticulum-golgi intermediate compartment protein 53; ERGIC53; ERGIC-53; ER-Golgi intermediate compartment 53 kDa protein; F5F8D; FMFD1; Gp58; intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose binding 1; lectin, mannose-binding, 1; LMAN1; MCFD1; MR60; P58; Protein ERGIC-53
Gene Symbols LMAN1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human LMAN1 (aa 36-85).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3998
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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