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  6. Invitrogen™ LIMK1 Recombinant Rabbit Monoclonal Antibody (23GB6425)

Invitrogen™ LIMK1 Recombinant Rabbit Monoclonal Antibody (23GB6425)
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Catalog No. MA553046
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100 μL
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MA553046 100 μL
MA553047 20 μL
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Catalog No. MA553046 Supplier Invitrogen™ Supplier No. MA553046
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Description

Rabbit Recombinant Monoclonal Antibody

LIMK1 Recombinant Monoclonal Antibody for ICC/IF, Western Blot

LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.

Specifications

Antigen LIMK1
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB6425
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LIMK1
Gene Accession No. P53667, P53668
Gene Alias EC 2.7.11.1; kinase LIMK1; KIZ-1; LIM domain kinase 1; lim kinase 1; LIM motif-containing protein kinase; LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing, protein kinase 1; Limk; LIMK1; LIMK-1
Gene Symbols LIMK1
Host Species Rabbit
Immunogen A synthesized peptide derived from human LIM Kinase 1 (1-57AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16885, 3984
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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