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Invitrogen™ LFNG Recombinant Rabbit Monoclonal Antibody (23GB6595)

Catalog No. MA553073
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100 μL
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MA553073 20 μL
MA553072 100 μL
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Catalog No. MA553073 Supplier Invitrogen™ Supplier No. MA553073
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Rabbit Recombinant Monoclonal Antibody

LFNG Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).

Specifications

Antigen LFNG
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB6595
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LFNG
Gene Accession No. O09010, Q8NES3
Gene Alias AW061165; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe; lunatic fringe gene homolog; MGC128664 protein; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3
Gene Symbols LFNG
Host Species Rabbit
Immunogen A synthesized peptide derived from human Lunatic Fringe (350-379AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16848, 3955
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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