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Thermo Scientific™ LanthaScreen™ Tb-PY20 Antibody Kit 
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
Supplier: Thermo Scientific™ PV3552
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in combination with Fluorescein-poly-GT (Cat. No. PV3610) or Fluorescein-poly-GAT (PV3611) to evaluate inhibitors in medium to high throughput screening applications.
Specifications
| Tyrosine kinases | |
| Tb (Terbium)/FITC/Lanthanide Chelates | |
| 25 μg | |
| Kinase Antibodies and Immunoassays | |
| 1 Kit | |
| 150,000 Da | |
| 384-well Plate | |
| Dry Ice | |
| Signal Transduction | |
| Tyrosine Kinases | |
| ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70 |
| 0.45 mg/mL | |
| 150 kDa | |
| RUO | |
| Primary | |
| Terbium-labeled anti-pY20 antibody in HEPES buffered saline. Store at -20°C. | |
| Biochemical terbium phospho-specific activity | |
| 340/490, 520 nm | |
| End Point | |
| ABL1 G250E, CSF1R, CSK, EPHA5, KIT, PDGFRA T674I, PDGFRA V561D, PTK6, RET Y791F, SYK, TYRO3, ZAP70, FGFR1, FGFR2, BLK, EGFR, EPHB2, FGFR4, IGF1R, LYNA, MATK, MERTK, NTRK3, RET V804L, ROS1, TEK, TTK, FLT1, MUSK, SRCN1, TEC, ABL1 E255K, BMX, EPHA4, FYN, PTK2, PTK2B, RET, ABL1 T315I, EPHA3, EPHB4, FLT3, FLT4, INSR, LCK, YES1, EGFR L858R, ERBB4, KDR, MET, TNK2, ABL1, ABL2, AXL, FGFR3, FGFR3 K650E, FGR, HCK, KIT V654A, EPHA1, EPHA8, EPHB3, INSRR, LYNB, MST1R, NTRK1, PDGFRA D842V, SRMS, EGFR L861Q, EPHA2, FER, LTK, PDGFRA, PDGFRB, EGFR T790M, EPHA7, EPHB1, MET M1250T, FRK, ITK, FLT3 D835Y, SRC, ABL1 Y253F, BTK, DDR2, FES, KIT T670I, TXK, ERBB2, NTRK2 | |
| TR-FRET | |
| LanthaScreen |
For Research Use Only. Not for use in diagnostic procedures.