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  6. TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™

TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS1485PABX
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Quantity:
200 μL
500 μL
Conjugate:
Unconjugated
Form:
Concentrated
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Conjugate Form Concentration
MS1485PABX 200 μL Unconjugated Concentrated 1mg/mL
MS1485P1 500 μL Unconjugated Concentrated 200μg/mL
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Catalog No. MS1485PABX Supplier Thermo Fisher Scientific Supplier No. MS1485PABX
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Description

Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 3A4

Isotype: IgG2a/κ

Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein

Molecular Weight: 21kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen TIMP-2 Ab-5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3A4
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen A synthetic peptide from the N-terminal region of human TIMP-2 protein
Quantity 200 μL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Primary or Secondary Primary
Target Species Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat
Form Concentrated
Isotype IgG2a κ
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