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MHC II (HLA-DR) Ab-1 Mouse Monoclonal Antibody, Epredia™
Epredia™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.
Supplier: Thermo Fisher Scientific MS133P1ABX
Description
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an α chain (36 kDa) and a β chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.Host Species: Mouse
Clone: LN3
Isotype: IgG2b
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Activated human peripheral blood mononuclear cells
Molecular Weight: 36kDa (α-chain) and 27kDa (β-chain)
Positive Control: Tonsil/lymph node
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry
- Flow Cytometry
Note:
USA: RUO; Int'l: RUO
Spécifications
| MHC II (HLA-DR) Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| Hematopoietic | |
| Human | |
| IgG2b |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| LN3 | |
| Unconjugated | |
| Activated human peripheral blood mononuclear cells | |
| RUO | |
| Primary | |
| Concentrated |