missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. HER-2/c-erbB-2/neu Ab-4 Mouse Monoclonal Antibody, Epredia™

HER-2/c-erbB-2/neu Ab-4 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS301P1
Change view
Click to view available options
Quantity:
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
200μg/mL
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Conjugate Concentration
MS301P1 500 μL Unconjugated 200μg/mL
MS301B1 500 μL Biotin 200μg/mL
MS301B 1 mL Biotin 200μg/mL
MS301P 1 mL Unconjugated 200μg/mL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
Catalog No. MS301P1 Supplier Thermo Fisher Scientific Supplier No. MS301P1

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Description

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (∽90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Applications Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone N12
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Intact SKBR-3 breast cancer cells
Quantity 500 μL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
Show More Show Less