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  6. Invitrogen™ KSR1 Recombinant Rabbit Monoclonal Antibody (23GB6290)

Invitrogen™ KSR1 Recombinant Rabbit Monoclonal Antibody (23GB6290)

Catalog No. MA553957
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100 μL
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MA553957 20 μL
MA553956 100 μL
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Catalog No. MA553957 Supplier Invitrogen™ Supplier No. MA553957
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Description

Rabbit Recombinant Monoclonal Antibody

KSR1 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [UniProt].

Specifications

Antigen KSR1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB6290
Concentration 0.375 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KSR1
Gene Accession No. Q8IVT5
Gene Alias AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2
Gene Symbols KSR1
Host Species Rabbit
Immunogen A synthesized peptide derived from human KSR1 (880-923AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 360573, 8844
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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