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Invitrogen™ KLRG1 Monoclonal Antibody (2F1), Brilliant Violet™ 711, eBioscience™, Invitrogen™

Syrian Hamster Monoclonal Antibody

Supplier:  Invitrogen™ 407589382

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Catalog No. 40-758-9382


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Description

Description

KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
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