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Invitrogen™ JNK1/JNK2/JNK3 Polyclonal Antibody
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Catalog No. PIPA5116884
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PIPA5116884 100 μL
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Catalog No. PIPA5116884 Supplier Invitrogen™ Supplier No. PA5116884
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Rabbit Polyclonal Antibody

Positive Samples: SH-SY5Y, Mouse brain, Rat brain Immunogen sequence: MSRSKRDNNF YSVEIGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAILER NVAIKKLSRP FQNQTHAKRA YRELVLMKCV NHKNIIGLLN VFTPQKSLEE FQDVYIVMEL MDANLCQVIQ MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTAGTSF MMTPYVVTRY YRAPEVILGM GYKENVDLWS VGCIMGEMVC HKILFPGRDY IDQWNKVIEQ LGTPCPEFMK KLQPTVRTYV ENRPKYAGYS FEKLFPDVLF PADSEHNKLK ASQARDLLSK MLVIDASKRI SVDEALQHPY INVWYDPSEA EAPPPKIPDK QLDEREHTIE EWKELIYKEV MDLEERTKNG.

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

Specifications

Antigen JNK1/JNK2/JNK3
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.84 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene MAPK9
Gene Accession No. P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Gene Alias AI849689; AI851083; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; janus kinase 1; janus kinase 2; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; Jnk2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; Mapk8; Mapk9; MGC137545 protein; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alpha; p54aSAPK; p54-beta; p54bSAPK; Phospho-JNK; PRKM10; Prkm8; PRKM9; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPb; SAPK; SAPK gamma; SAPK(beta); SAPK/Erk/kinase 2; SAPK1; SAPK1a; SAPK1B; SAPK1c; SAPK-alpha; SAPK-beta; SAPKC; Serk2; si:ch211-247j9.2; stress activated protein kinase alpha II; Stress activated protein kinase beta; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1b; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; stress-activated protein kinase JNK2; Stress-activated protein kinase JNK3; zgc:123234
Gene Symbols MAPK10, MAPK8, MAPK9
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human JNK1/2/3 (NP_6206371).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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