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Invitrogen™ IRF4 Monoclonal Antibody (3E4), Brilliant Violet™ 650, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Supplier: Invitrogen™ 416985880
Description
The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.Specifications
| IRF4 | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| Q15306, Q64287 | |
| IRF4 | |
| Affinity chromatography | |
| RUO | |
| 16364, 3662 | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| 3E4 | |
| Brilliant Violet 650 | |
| IRF4 | |
| AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP | |
| Rat | |
| 25 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 κ |