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Invitrogen™ IRAK-M Recombinant Rabbit Monoclonal Antibody (23GB875)
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Catalog No. MA554018
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100 μL
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MA554018 100 μL
MA554019 20 μL
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Catalog No. MA554018 Supplier Invitrogen™ Supplier No. MA554018
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Rabbit Recombinant Monoclonal Antibody

IRAK-M Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.

Specifications

Antigen IRAK-M
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB875
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IRAK3
Gene Accession No. Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen A synthetic peptide of human IRAK3 (550-596AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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