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Invitrogen™ IRAK-M Monoclonal Antibody (6G9G2)
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Catalog No. PIMA538545
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Quantity:
100 μg
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Catalog No. Quantity
PIMA538545 100 μg
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Catalog No. PIMA538545 Supplier Invitrogen™ Supplier No. MA538545
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.

Specifications

Antigen IRAK-M
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6G9G2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene IRAK3
Gene Accession No. Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Mouse
Immunogen Purified recombinant fragment of human IRAK3 (aa: 454-596) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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