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Invitrogen™ Influenza A PB2 Polyclonal Antibody
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Catalog No. PIPA532220
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100 μL
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Catalog No. Quantity
PIPA532220 100 μL
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Catalog No. PIPA532220 Supplier Invitrogen™ Supplier No. PA532220

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Influenza A virus contains eight single stranded, negative sense RNAs. Each RNA is associated with viral RNA-dependent RNA polymerase which consists of PA, PB1 and PB2 proteins. PB1 is the subunit involved in the catalytic activity of nucleotide polymerization and is involved in the initiation of transcription. Both PB1 and PB2 can be crosslinked to synthetic RNA with the 3' terminal sequence of viral RNA. PB1 and PB2 may also be involved in recognition of the promoter and/or replication origin on template viral RNA. PB2 is the cap 1-recognition protein, which binds to the cap structure of host mRNA. The cap structure then acts as a primer for transcription to produce viral mRNA.

Specifications

Antigen Influenza A PB2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Alias Influenza PB2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of Influenza A virus PB2 (A/Puerto Rico/8/1934(H1N1)). The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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