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Invitrogen™ Infliximab Chimeric Recombinant Mouse Monoclonal Antibody (cA2 (Infliximab))
Mouse Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA551625
Description
Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.
Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-alpha, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-alpha blocker to disrupt the interaction of TNF-alpha with its receptors.Specifications
| Infliximab Chimeric | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| Mouse | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA, Flow Cytometry, Functional Assay | |
| cA2 (Infliximab) | |
| Unconjugated | |
| Remicade; TA-650 | |
| Purified recombinant human TNF (rTNF). | |
| 200 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |