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Invitrogen™ IL4R Polyclonal Antibody
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Catalog No. pipa5103142
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100 μL
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PIPA5103142 100 μL
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Catalog No. PIPA5103142 Supplier Invitrogen™ Supplier No. PA5103142
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IL4R/CD124.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.

Specifications

Antigen IL4R
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IL4R
Gene Accession No. P16382, P24394
Gene Alias 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Gene Symbols IL4R, Il4ra
Host Species Rabbit
Immunogen A synthesized peptide derived from human IL4R(Accession P24394), corresponding to amino acid residues V94-S144.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16190, 3566
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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