missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ IL2RG Recombinant Rat Monoclonal Antibody (3E12)
Rat Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA551816
Description
This conformation-dependent antibody binds to the murine common gamma-chain, shared by the IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 receptor complexes. It recognises an epitope located in a membrane-proximal portion of the common gamma-chain, near Arg-197 of domain 2. This antibody does not cross-react with COS7 cells transfected with rat common gamma-chain cDNA.
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.Specifications
| IL2RG | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| P34902 | |
| IL2RG | |
| This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing murine cytoplasmic-tailless IL-2R common gamma-chain (YB2/0-myt). | |
| 200 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2b κ |
| Flow Cytometry, Inhibition Assays, Immunoprecipitation | |
| 3E12 | |
| Unconjugated | |
| IL2RG | |
| [g]c; Ab2-183; CD132; CD132 antigen; CIDX; common cytokine receptor gamma chain; cytokine receptor common subunit gamma; gamma(c); gammaC; gc; IL-2 receptor subunit gamma; IL2R gamma; IL-2R subunit gamma; IL2RG; IL-2RG; IMD4; interleukin 2 receptor subunit gamma; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); interleukin 2 receptor, gamma chain; Interleukin-2 receptor subunit gamma; p64; SCIDX; SCIDX1 | |
| Rat | |
| Protein A | |
| RUO | |
| 16186 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |