missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ IL-6 Receptor Monoclonal Antibody (B-R6)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ AHR0061
Description
Specificity: Recognizes the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein Biological Activity: Inhibits IL-6 induced proliferation of XG-1 cells.
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.Chemical Identifiers
| IL-6 Receptor | |
| 4.0 mg/mL | |
| ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization | |
| Unconjugated | |
| Mouse | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| P08887 | |
| 3570 | |
| CHO cells transfected with cDNA corresponding to the gp80 IL-6 receptor gene. | |
| Antibody |
| B-R6 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Monoclonal | |
| Liquid | |
| IgG1 κ | |
| Human | |
| IL6R | |
| CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991 | |
| IL6R | |
| Primary | |
| Purified |
Specifications
| IL-6 Receptor | |
| Monoclonal | |
| 4.0 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| P08887 | |
| IL6R | |
| CHO cells transfected with cDNA corresponding to the gp80 IL-6 receptor gene. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization | |
| B-R6 | |
| Unconjugated | |
| IL6R | |
| CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991 | |
| Mouse | |
| Purified | |
| RUO | |
| 3570 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |