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Invitrogen™ IL-10 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA585660
Description
Keep as concentrated solution. Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%). Positive Control: 293T, human IL10-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.Chemical Identifiers
| IL-10 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse | |
| IL10 | |
| CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF | |
| IL10 | |
| Primary | |
| Antigen affinity chromatography |
| 1.17 mg/mL | |
| ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P18893, P22301 | |
| 16153, 3586 | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human IL10. The exact sequence is proprietary. | |
| Antibody |
Specifications
| IL-10 | |
| Polyclonal | |
| Unconjugated | |
| IL10 | |
| CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 16153, 3586 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot | |
| 1.17 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P18893, P22301 | |
| IL10 | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human IL10. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |