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Invitrogen™ IkB epsilon Monoclonal Antibody (OTI4D1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA527341
Description
IkB epsilon Monoclonal Antibody for Western Blot
NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT (see STAT6, MIM 601512), AP1 (JUN, MIM 165160), and NFAT (see NFATC1, MIM 600489).Chemical Identifiers
| IkB epsilon | |
| 1 mg/mL | |
| Western Blot | |
| Unconjugated | |
| Mouse | |
| RUO | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O00221 | |
| 4794 | |
| Full length human recombinant protein of NFKBIE produced in E.coli. | |
| Antibody |
| OTI4D1 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Monoclonal | |
| Liquid | |
| IgG2a | |
| Human | |
| Nfkbie | |
| ikappaBepsilon; I-kappa-B-epsilon; IkB epsilon; IKBE; IkB-E; IkBepsilon; ikB-epsilon; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; NFKB inhibitor epsilon; NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; Slc35b2; solute carrier family 35, member B2 | |
| Nfkbie | |
| Primary | |
| Affinity Chromatography |
Specifications
| IkB epsilon | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O00221 | |
| Nfkbie | |
| Full length human recombinant protein of NFKBIE produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Western Blot | |
| OTI4D1 | |
| Unconjugated | |
| Nfkbie | |
| ikappaBepsilon; I-kappa-B-epsilon; IkB epsilon; IKBE; IkB-E; IkBepsilon; ikB-epsilon; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; NFKB inhibitor epsilon; NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; Slc35b2; solute carrier family 35, member B2 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 4794 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |