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Invitrogen™ ID4 Polyclonal Antibody

Description
Immunogen sequence: MKAVSPVRPS GRKAPSGCGG GELALRCLAE HGHSLGGSAA AAAAAAAARC KAAEAAADEP ALCLQCDMND CYSRLRRLVP TIPPNKKVSK VEILQHVIDY.
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
Specifications
Specifications
| Antigen | ID4 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.54 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | Id4 |
| Gene Accession No. | P41139 |
| Gene Alias | bHLHb27; cb547; Class B basic helix-loop-helix protein 27; DNA-binding protein inhibitor ID-4; fb77d04; hypothetical protein LOC664761; ID4; Id-4; Idb4; Inhibitor of differentiation 4; inhibitor of DNA binding 4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; inhibitor of DNA binding 4, HLH protein; sb:cb547; wu:fb77d04; zgc:123214 |
| Gene Symbols | Id4 |
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